Methanol, Ethanol and Iso-propyl Alcohol (IPA) have fairly similar cleaning performance. IPA is preferred because it evaporates more slowly than methanol and ethanol and doesn’t have the regulatory issues of ethanol. It’s available in high purity for a relatively low cost.
Acetone is a stronger solvent, in that it will dissolve a wider range of organics. The issue with cleaning with acetone (and any strong solvent for that matter) is that whatever you dissolve is left behind when the solvent evaporates. This is why acetone usually leaves a film. Even more frustrating is that those films are sometimes not easy to dissolve again.
I have always taught that solvent cleaning should be a progression from weakest to strongest back to weakest. The idea is to first rinse away as much as possible with IPA or water (eg you don’t want to be trying to dissolve chunks of dust), then dissolve what remains with acetone, (or toluene, or heptane) but DON’T LET THAT SOLVENT DRY as it will leave behind a film of everything you dissolved. Instead, you want to displace the acetone (or whatever) with IPA, then blow the IPA off with compressed air. It’s generally not possible to blow off fast evaporating solvents, so that’s why we displace them first with slow evaporating solvents (or water).
Personally, I wouldn’t want to use anything stronger than IPA on a leather strop. I have a spray bottle of IPA/DI water that I use to wet the surface and then wipe it with a paper towel.
A good option for degreasing is to use an electronic cleaning spray.